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Acral Mutiliation Syndrome (AMS) is a severe neurological disorder found in several Pointer and Spaniel breeds.
Working days 10
Specifiche
| Breeds | Cane da ferma tedesco a pelo corto, Cocker spaniel inglese, Springer Spaniel inglese, English Pointer, French Spaniel |
|---|---|
| Gene | |
| Organ | |
| specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | |
| Chromosome | |
| Also known as | |
| Year Published |
Informazioni generali
Acral Mutiliation Syndrome (AMS) is a severe neurological disorder found in several Pointer and Spaniel breeds. AMS causes a loss of pain sensitivity in the limbs, often leading to affected dogs aggressively licking or biting at their own paws, severely injuring them without noticing. The disorder is caused by a recessive mutation to the gene GDNF.
Caratteristiche cliniche
Onset of AMS symptoms occurs at approximately 4 months of age. Affected puppies lose sensation in their paws and often lick or bite at them. This results in ulcers, claw loss, painless bone fractures and ultimately amputated toes. There is no loss of motor control or coordination.
Informazioni aggiuntive
Riferimenti
Pubmed ID: 28033318
Omia ID: 1514
Prodotti correlati
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- Yorkshire Terrier
- L2HGDH
- Sistema nervoso
-
- Golden Retriever
- NVT
-
- Pug
- MYH9
- Apparati multipli
-
- Shetland Sheepdog
- BBS2
- Organi di senso
