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Coat colour in dogs is controlled by a wide range of different genes working together.
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Specifiche
| Breeds | |
|---|---|
| Gene | |
| Organ | |
| specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | |
| Chromosome | |
| Also known as | |
| Year Published |
Informazioni generali
Coat colour in dogs is controlled by a wide range of different genes working together. These genes are often referred to as ‘loci’. The Dilution, or D-Locus, corresponds to the gene for melanophilin, MLPH, which is involved in the distribution of pigment. Mutations of the D-Locus result in a ‘dilution’ of dark coat colours, turning them lighter and more silvery.
Any combination of two mutant alleles will result in a diluted coat. This variant of the D-Locus mutation, designated as d^1, is the most commonly observed one in dogs.
Caratteristiche cliniche
Il colore dei capelli e del naso viene diluito, il colore degli occhi si schiarisce in ambra. L'allele D è dominante e non ha un effetto sul colore del mantello. Solo nei cani con due copie di un allele recessivo d, il colore del mantello viene diluito. Il nero si diluisce in grigio, chiamato anche blu o carbone. Il mantello varia dall'argento al quasi nero, ma tutti hanno un naso blu. Cioccolato/ marrone / fegato diluisce in lilla / abbronzatura leggera / Isabella, il loro naso varia dal rosa, fegato a isabella. Rosso/giallo/crema diluisce in champagne.
Informazioni aggiuntive
Coat colour is an intricate trait that involves a combination of multiple different genes. Testing for a range of different loci will give the most complete prediction of a dog's coat colour genetics.
Additional, undiscovered variants of the D-Locus mutation are likely to exist.
Riferimenti
Pubmed ID: 17519392
Omia ID: 31
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