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The Dominant White coat colour pattern in horses can be caused by any in a wide array of related mutations.
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Specifiche
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Gene | |
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specimen | Hair, Blood EDTA, Blood Heparin, Semen, Tissue |
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Informazioni generali
The Dominant White coat colour pattern in horses can be caused by any in a wide array of related mutations. The resulting pattern can vary anywhere between white markings on the face and legs, up to a completely white coat. Depending on both breed and pattern, variants of the Dominant White phenotype may be referred to as Splashed White, White Spotting, Tobiano or Sabino, among others.
The variant analysed in this test, known as Tobiano, is caused by a dominant mutation to the gene KIT. The variant is present in approximately 86% of Lewitzer horses with tobiano patterning, and has also been found in the Irish Cob.
Caratteristiche cliniche
Il pattern a macchie bianche Tobiano si caratterizza da macchie ovali o rotonde generali e distinte di pelle e pelo depigmentati. La depigmentazione si estende verso il basso sopra il collo e il torace, che può essere visto come uno scudo. L'entità della depigmentazione può variare da circa il 20% all'80% delle superfici del corpo. Il spotting pattern presente alla nascita e stabile per tutta la vita.
Informazioni aggiuntive
Coat colour is an intricate trait that involves a combination of multiple different genes. Testing for a range of different loci will give the most complete prediction of a horse's coat colour genetics.
Dominant White can be caused by a wide range of mutations. A white-patterned horse that tests as unaffected for a particular mutation will almost certainly be affected by a different one.
Riferimenti
Pubmed ID: 18410476
Omia ID: 209