€57,48 €47,50 IVA esclusa
Le macchie bianche e bianche dominanti sono controllate dal gene KIT.
Working days 20
Specifiche
| Breeds | |
|---|---|
| Gene | |
| Organ | |
| specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | |
| Chromosome | |
| Also known as | |
| Year Published |
Informazioni generali
Le macchie bianche e bianche dominanti sono controllate dal gene KIT. Il bianco dominante è anche descritto come il W-locus e white spotting come S-locus. Il gene KIT ha tre varianti (alleli). L’allele DW è dominante sugli alleli Ws e N; allele Ws è dominante sull’allele N.
Caratteristiche cliniche
The dominant allele DW results in a white coat colour. One or two copies of the DW allele will result in a white-coated cat with varying degrees of hearing impairment. The allele Ws in white spotting and the allele N has no effect on the coat colour.
Informazioni aggiuntive
The gene/genes controlling the pattern of White Spotting is still unknown. Additionally, not all white spots or patterns result from the KIT-gene as other genes can also have mutations that result in depigmentation phenotypes. Dominant White is distinct from albinism (C-locus) which results from a mutation in the TYR gene that has no known impact on hearing.
Riferimenti
Pubmed ID: 25085922
Omia ID: 209
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