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Dilated Cardiomyopathy (DCM) is a disorder characterised by enlargement of the heart (especially of the left ventricle), poor myocardial contractility, and congestive heart failure.
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Specifiche
| Breeds | |
|---|---|
| Gene | |
| Organ | |
| specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | |
| Also known as | |
| Year Published |
Informazioni generali
Dilated Cardiomyopathy (DCM) is a disorder characterised by enlargement of the heart (especially of the left ventricle), poor myocardial contractility, and congestive heart failure. This specific test detects a mutation to the gene PDK4 that has been linked to an increased risk for the disorder in the Doberman.
Caratteristiche cliniche
DCM is an enlargement of the heart that can result in decreased heart function and abnormal heart rhythm. Clinical signs of heart failure due to DCM include fainting or collapse, weight loss, breathlessness, fluid retention in the abdomen, and sudden death due to cardiac arrest.
Informazioni aggiuntive
The mutation in this test should be considered a risk factor. It is associated with the disorder, but does not necessarily guarantee it.
Riferimenti
Pubmed ID: 22447147
Omia ID: 162
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