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Hereditary Equine Regional Dermal Asthenia (HERDA), also known as Hyperelastosis Cutis (HC) is a tissue disorder in the American Quarter Horse that causes loose, fragile skin.

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Specifiche

Breeds

,

Gene

Organ

specimen

Hair, Blood EDTA, Blood Heparin, Semen, Tissue
Mode of Inheritance

Chromosome

Also known as

Year Published

Informazioni generali

Hereditary Equine Regional Dermal Asthenia (HERDA), also known as Hyperelastosis Cutis (HC) is a tissue disorder in the American Quarter Horse that causes loose, fragile skin. The disorder is caused by a recessive mutation to the gene PPIB.

While the disorder occurs primarily in the American Quarter Horse, it has also been observed in Arabian and American Paint horses with Quarter Horse ancestry.

Caratteristiche cliniche

The primary symptom of HERDA is loose skin that can be described as stretchy or elastic. The skin is more fragile than normal, sloughing easily and causing ulcers, hematomas and scarring. The symptoms usually become apparent between 1 and 2 years of age, when the horse starts its saddle training. Owners typically elect for euthanasia on humane grounds.

Informazioni aggiuntive

Riferimenti

Pubmed ID: 17498917

Omia ID: 327

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