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Lavender Foal Syndrome (LFS, also called Lethal Coat Colour Dilution) is a severe, recessively-inherited neurological disorder in Arabian horses.

Working days 10

Specifiche

Breeds

Gene

Organ

specimen

Hair, Blood EDTA, Blood Heparin, Semen, Tissue
Mode of Inheritance

Chromosome

Also known as

Year Published

Informazioni generali

Lavender Foal Syndrome (LFS, also called Lethal Coat Colour Dilution) is a severe, recessively-inherited neurological disorder in Arabian horses. Affected foals are often stillborn, and suffer greatly if even if they survive, being unable to stand or nurse properly. Surviving lavender foals are therefore usually euthanized on humane grounds. The condition is named for the light, “diluted” coat colour that affected foals have. LFS is caused by a mutation to the gene MYO5A.

Caratteristiche cliniche

LFS typically results in stillbirth. Surviving foals cannot stand, and in some cases are unable to roll to lie upright. Other features include a backwards-arched neck, stiffly extended legs, seizures, and a distinctive lightened coat, which can be described as pale gray, pewter, light chestnut or lavender.

Informazioni aggiuntive

Riferimenti

Pubmed ID: 20419149

Omia ID: 1501

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