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Upper Airway Syndrome (NTUAS) is a breathing disorder found in dogs.
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Specifiche
| Razza | |
|---|---|
| Gene | |
| Cromosoma | 13 |
| Mutation | c.2786G>A |
| Tipo di Ereditarietà | Sconosciuto |
| Organo | |
| Campione | Tampone, Sangue in EDTA, Sangue in Eparina, Seme, Tessuto |
| Also known as | UAS |
Informazioni generali
Upper Airway Syndrome (NTUAS) is a breathing disorder found in dogs. The disorder is linked to a mutation to the gene ADAMTS3. The mutation has been found in, amongst others, Norwich Terrier, French Bulldog and Staffordshire Bull Terrier.
NTUAS has an symptoms overlap with Brachycephalic Obstructive Airway Syndrome (BOAS), a disorder that causes breathing difficulties in brachycephalic dogs.
The main issues in affected dogs include a slightly elongated soft palate, extra tissue in the throat, and structural changes in the larynx. These abnormalities, caused by the ADAMTS3 mutation, can lead to breathing difficulties of varying severity. Further research is needed to fully understand the range of symptoms.
Caratteristiche cliniche
I cani colpiti possono avere difficoltà respiratorie, spesso accompagnate da stridore (respiro sibilante o sbuffo). Altri possibili sintomi includono tonsille ingrossate o gonfie e collasso laringeo parziale. La diagnosi può essere difficile senza un esame laringoscopico.
Informazioni aggiuntive
Riferimenti
Pubmed ID: 31095560
Year published: 2019
Omia ID: 1893
Omia variant ID: 1084