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Dopamine is a so-called neurotransmitter.
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Specifiche
| Breeds | |
|---|---|
| Gene | |
| Organ | |
| specimen | Piuma, Sangue con EDTA, Sangue con Eparina |
| Mode of Inheritance | |
| Chromosome | |
| Also known as | |
| Year Published |
Informazioni generali
Dopamine is a so-called neurotransmitter. Many important physiological functions are mediated by dopamine and its receptors. The dopamine receptor type 4 (DRD4) gene has been scientifically proven to influence the racing performance of pigeons, making it a useful performance marker.
There are two point mutations in this gene: DRD4-Bst4CI (also known as DRD4-1 or DRD4a) and DRD4-MnlI (also known as DRD4-2 or DRD4b).
In this the DRD4-Bst4CI mutation is analysed, which has been linked to enhanced orientation and initiative. This mutation has a strong positive effect on races up to 600 km, particularly in heterozygous individuals. The other mutation is available as a separate test.
Caratteristiche cliniche
When only the DRD4-Bst4CI variant is heterozygous, there is a significant positive effect on performance in races up to 600 km. However, when both mutations are heterozygous, a combination referred to as double heterozygotes (CTCT individuals), these individuals are often among the best-performing pigeons in extremely long-distance flights.
Informazioni aggiuntive
Riferimenti
Pubmed ID: 26202371
Omia ID: