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Haemophilia B, also called Factor IX Deficiency or Christmas Disease, is a blood disorder that impairs clotting, which can lead to uncontrolled bleeding.
Giorni lavorativi10
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Specifiche
| Razza | |
|---|---|
| Gene | |
| Organo | |
| Campione | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Tipo di Ereditarietà | X-linked recessive |
| Cromosoma | X |
| Tipo di Ereditarietà | Factor IX |
| Anno di pubblicazione |
Informazioni generali
Haemophilia B, also called Factor IX Deficiency or Christmas Disease, is a blood disorder that impairs clotting, which can lead to uncontrolled bleeding. Haemophilia B is caused by an X-linked recessive mutation to the gene F9. There are many known variants of Haemophilia B, each specific to a particular dog breed. This variant occurs in the Cairn Terrier.
Caratteristiche cliniche
Affected dogs are prone to uncontrolled bleeding after injury or surgery, and may develop spontaneous bleeding. Blood analysis will confirm a lack of Factor IX activity and prolonged clotting times.
Informazioni aggiuntive
Riferimenti
Pubmed ID: 2481310
Omia ID: 438