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Dilated Cardiomyopathy (DCM) is a heart disorder characterised by enlargement of the heart (especially of the left ventricle), poor myocardial contractility, and congestive heart failure.
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Specifiche
| Razza | Manchester Terrier (Standard), Manchester Terrier (Toy), English Toy Terrier |
|---|---|
| Gene | |
| Organo | |
| Campione | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Tipo di Ereditarietà | Autosomal Recessive |
| Cromosoma | 27 |
| Tipo di Ereditarietà | JDCM |
| Anno di pubblicazione |
Informazioni generali
Dilated Cardiomyopathy (DCM) is a heart disorder characterised by enlargement of the heart (especially of the left ventricle), poor myocardial contractility, and congestive heart failure. This variant of the disorder, known as Juvenile Dilated Cardiomyopathy (JDCM), occurs in young dogs of the Manchester Terrier and English Toy Terrier breeds. It is caused by a recessive disorder to the gene ABCC9. The disorder is severe, and can cause sudden death of juvenile affected dogs.
Caratteristiche cliniche
Signs of congestive heart failure caused by DCM in affected dogs can include rapid or strained breathing while resting, restlessness, general weakness, decreased appetite and vomiting, pale gums and sudden death. Veterinary examination can provide a proper diagnosis. JDCM occurs in juvenile dogs, often before the age of 2 years.
Informazioni aggiuntive
Riferimenti
Pubmed ID: 37239348
Omia ID: 2710