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Squamous Cell Carcinoma (SCC) is one of the most common forms of cancer in horses.
Working days 10
Specifiche
| Breeds | |
|---|---|
| Gene | |
| Organ | |
| specimen | Hair, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | |
| Chromosome | |
| Also known as | |
| Year Published |
Informazioni generali
Squamous Cell Carcinoma (SCC) is one of the most common forms of cancer in horses. SCC eye tumours, which typically form at the edge of the sclera (eye white), are invasive and likely to cause vision loss, though they do not generally metastasize. In the Belgian Draft Horse, Connemara Pony and Haflinger, it has been found that horses carrying the mutation to the DDB2 gene analysed in this test are at increased risk of developing SCC.
Caratteristiche cliniche
Ocular SCC can develop in several different regions of the eye – including the eyelids, sclera and cornea – and symptoms are dependent on which parts have been (most) affected. Symptoms can include redness and tearing, swollen “cauliflower”-like sclerae, and the formation of tumors and lesions. SCC can cause vision impairment/loss and, in extreme cases, severely threaten the horse’s life.
Informazioni aggiuntive
The mutation in this test should be considered a risk factor. It is associated with the disorder, but does not necessarily guarantee it.
Riferimenti
Pubmed ID: 28425625
Omia ID: 735
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