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Cats have several different possible serotypes (blood types): Type A, Type B and the more uncommon Type AB (sometimes known as Type C).
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Specifiche
Breeds | |
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Gene | |
Organ | |
specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
Mode of Inheritance | |
Chromosome | |
Year Published |
Informazioni generali
Cats have several different possible serotypes (blood types): Type A, Type B and the more uncommon Type AB (sometimes known as Type C). Type A is “normal”; Types B and AB can be caused by a number of recessive mutations to the gene CMAH.
Besides being relevant for medical issues such as blood transfusion, a cat’s serotype is significant for breeding. If a kitten with Serotype A is born to a mother with Serotype B, it is at risk from the A-targeting antibodies in the mother’s milk. This causes a potentially lethal reaction known as Feline Isoerythrolysis Neonatalis (IN) or “Fading Kitten Syndrome”.
This test analyses for the rare mutation a^c, which causes blood type AB. The a^c allele is recessive to N (Type A), but dominant to b (Type B).
Caratteristiche cliniche
Il sistema del gruppo sanguigno A /B è clinicamente importante nei gatti perché l'allevamento non corrispondente e le trasfusioni possono causare reazioni emolitiche potenzialmente letali senza previa sensibilizzazione. Pertanto, una caratterizzazione genetica completa di tutti i tipi di sangue felino è fondamentale in modo che i test genetici possano segnalare accuratamente il gruppo sanguigno di un individuo.
Informazioni aggiuntive
Due to the many possible mutations that can cause blood type B, it is not always possible to identify a cat's blood type through genetics alone. The serological test (K712) directly determines blood type. This test must be done with a blood sample, rather than a saliva swab.
Riferimenti
Pubmed ID: 27171395
Omia ID: 119