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Thrombocytopenia is a blood disorder in which the body produces abnormally low levels of thrombocytes (blood platelets), which are responsible for clotting.

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Specifiche

Breeds

,

Gene

Organ

specimen

Swab, Blood EDTA, Blood Heparin, Semen, Tissue

Mode of Inheritance

Chromosome

Year Published

Informazioni generali

Thrombocytopenia is a blood disorder in which the body produces abnormally low levels of thrombocytes (blood platelets), which are responsible for clotting. Depending on the variant, symptoms may range from prolonged breeding times to an apparently healthy animal.

This variant of the disorder, sometimes called Macrothrombocytopenia (MTP), is found in the Norfolk Terrier and Cairn Terrier, and is caused by a recessive mutation to the gene TUBB1.

Caratteristiche cliniche

Affected dogs are clinically healthy, but blood tests will reveal a lowered platelet count. A related version occurs in the Cavalier King Charles Spaniel.

Informazioni aggiuntive

Riferimenti

Pubmed ID: 25060661

Omia ID: 2434

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