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Dominant Blue Eyes (DBE) in cats are typically associated with a lack of melanin in the iris.
Working days 10
Only available in bundles
Specifiche
| Breeds | |
|---|---|
| Gene | |
| Organ | |
| specimen | Tampone, Sangue in EDTA, Sangue in Eparina, Seme, Tessuto |
| Mode of Inheritance | |
| Chromosome | |
| Also known as | |
| Year Published |
Informazioni generali
Dominant Blue Eyes (DBE) in cats are typically associated with a lack of melanin in the iris. It is often due to genetics and is commonly seen in certain breeds. One of the genes involved in this trait is the Paired Box 3 (PAX3) gene. Mutations in the gene can result in white spotting, deafness, pigmentary disturbances in one or two eyes and in some cases also embryonic or fetal lethality. The tested mutation for the Celestial line is characterised by an autosomal dominant inheritance with variable expressivity and incomplete penetrance for both white spotting and blue eyes.
There are multiple mutations known. The variant tested here is found in the Celestial Maine Coon line, Siberian and Celestial cats.
Caratteristiche cliniche
I gatti con questa mutazione potrebbero mostrare uno o due occhi azzurri o occhi colorati e macchie bianche minime. Questo non indica necessariamente problemi di salute sottostanti. In diverse linee di riproduzione felina la sordità è stata identificata come associata a questo tratto.
Informazioni aggiuntive
Consulting with a researcher involved in the study of mutations for blue eyes in cats revealed that this test is specific to the Celestial Maine Coon line. In the publication on this research, only this specific line is mentioned, and there is no scientific evidence for the presence of this mutation in the regular Maine Coon population.
Riferimenti
Pubmed ID: 38644700
Omia ID: 1688